Rapid-test sensitivity for novel swine-origin pandemic influenza A

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Swine- Origin Influenza A (H1N1) Pandemic Revisited

Since the beginning of January 2008 sporadic cases of infections in humans caused by influenza A (H1N1) virusresistant to available anti-influenza drugs have been reported worldwide [1,2]. The World Health Organization (WHO) in its report published on 18 March 2009 indicated that during weeks 1-4 (28 December 08-24 January 09), the level of overall influenza activity in the world increased. Dur...

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rapidSTRIPE H1N1 test for detection of the pandemic swine origin influenza A (H1N1) virus.

The rapidSTRIPE H1N1 test, based on a nucleic acid lateral-flow assay, has been developed for diagnosis of a swine-origin influenza A (H1N1) virus. This test is simple and cost-effective and allows specific detection of the S-OIV A (H1N1) virus from swab sampling to final detection on a lateral-flow stripe within 2 to 3 h.

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Analytical sensitivity of rapid influenza antigen detection tests for swine-origin influenza virus (H1N1).

BACKGROUND A novel swine origin influenza virus (S-OIV) (H1N1) is spreading worldwide and threatens to become pandemic. OBJECTIVES Determine analytical sensitivity of selected commercially available rapid influenza antigen detection tests in detecting S-OIV H1N1. STUDY DESIGN Serial dilutions of two S-OIV isolates, one seasonal influenza A (H1N1) isolate and a nasopharyngeal aspirate from a...

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Poor Clinical Sensitivity of Rapid Antigen Test for Influenza A Pandemic (H1N1) 2009 Virus

Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription-PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen-based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test-positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic.

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ژورنال

عنوان ژورنال: Journal of the Formosan Medical Association

سال: 2012

ISSN: 0929-6646

DOI: 10.1016/j.jfma.2011.06.018